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Professor Zach Murphy will present on Venous Thromboembolism, including Pulmonary Embolism (PE) and Deep Vein Thrombosis (DVT). We will be going into detail on the following main objectives:
1. Definition and Classification of Venous Thromboembolism
- Acquire an in-depth understanding of Venous Thromboembolism, a condition involving the formation of blood clots in the venous system.
- Explore the two main types of VTE: Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).
2. Pathophysiology and Etiologies
- Uncover the underlying mechanisms leading to VTE, focusing on the triad of stasis, hypercoagulability, and endothelial injury.
- Investigate common risk factors such as surgery, malignancy, immobility, and inherited clotting disorders.
3. Clinical Manifestations and Presentation
- Identify key signs and symptoms for DVT, including leg swelling, pain, and erythema, and for PE, such as dyspnea, chest pain, and hemoptysis.
- Recognize how to differentiate between DVT and PE based on clinical presentation and risk factors.
4. Diagnostic Criteria and Tools
- Familiarize yourself with the diagnostic modalities available, such as ultrasound for DVT and CT pulmonary angiography for PE.
- Learn about risk stratification tools like the Wells Criteria and the Pulmonary Embolism Rule-out Criteria (PERC).
5. Initial Management Strategies
- Understand evidence-based approaches for immediate management, including anticoagulation therapy and supportive care.
- Explore the indications for pharmacologic thrombolysis and mechanical thrombectomy.
6. Definitive Management Approaches
- Examine long-term treatment options, such as vitamin K antagonists and direct oral anticoagulants (DOACs).
- Evaluate the criteria for treatment duration and the role of inferior vena cava (IVC) filters.
7. Complications and Prognosis
- Discuss potential complications like post-thrombotic syndrome, chronic thromboembolic pulmonary hypertension, and recurrent VTE events.
- Consider prognostic factors, including the presence of comorbid conditions, the extent of clot burden, and response to initial treatment.
Table of Contents:
0:00 Lab
0:07 Venous Thromboembolism Introduction
0:14 Pathophysiology of DVT
5:01 Issues with DVT
6:03 Diagnostic Approach to DVT
9:09 Treatment of DVT
10:34 Pathophysiology of Pulmonary Embolism
11:59 Issues with Pulmonary Embolism
14:23 Diagnostic Approach to Pulmonary Embolism
20:39 Treatment of Pulmonary Embolism
23:24 Comment, Like, SUBSCRIBE!